Copy
An online news cutting service that specialises in news relating to polio and post-polio issues; disability and other health-related issues may also be covered.
ppn
Contents:
Updates from

Post-Polio News RSS Feed

UK: England: Britain’s Preparing For A Second Wave. But Shielders Like Me Are Being Left Behind | The Huffington Post.

[28/09/2020] Jenni Elbourne writes:

I never really stopped shielding, but Boris Johnson simply saying ‘you do not need to shield’ feels like another way of saying ‘we’re not going to protect you.’

The country is coming to terms with the real threat of a ‘second wave’ and adapting to the latest government guidelines. For thousands of people like me who are clinically extremely vulnerable to coronavirus, it marks the beginning of a new and even more difficult phase in our national crisis. 

A year ago, as a healthy 33-year-old I could never have imagined what the universe had in store for me. First, I was diagnosed with leukaemia and spent the autumn having intensive chemotherapy. Then in February I learned I would need a stem cell transplant, around the same time as the first few cases of Covid-19 were confirmed in the UK. I spent March in hospital having my failing immune system completely wiped out by radiotherapy, and had my lifesaving transplant on the day the WHO declared a global pandemic. Getting home after weeks in isolation should have been a relief, but with the virus killing hundreds of people every day, it was obvious my recovery wasn’t going to be how I’d imagined it.  

I was advised to shield from the beginning of lockdown until 1 August, when shielding officially stopped in England. This advice has not changed or been broken down according to medical conditions, despite research showing that people with blood cancer are at higher risk of becoming seriously ill from coronavirus than almost any other condition. Personally I’ve continued to limit my activities to hospital visits and country walks, because I can’t bear the thought of catching the virus now, after all the sacrifices I’ve already made just to be alive.

I’ve not been to the pub since Christmas, so I don’t have much sympathy for anyone who’s complaining about a 10pm curfew.

As for the guidelines that were issued, the vast majority have no bearing on my life right now. I’ve not been to the pub since Christmas, so I don’t have much sympathy for anyone who’s complaining about a 10pm curfew, or only being allowed to meet five of their friends there. 

Where work is concerned, the government made a u-turn on their previous advice to go back to the office, and now say everyone should work from home ‘if they can.’ I welcome this as a way to reduce the spread of the virus, but it is of little comfort to people who are clinically vulnerable and have jobs that can’t be done remotely. We need the legal right to work from home, or a specific furlough scheme to cover jobs where that’s not possible. In my own case, having previously been self-employed in an industry that’s no longer functioning, I’m looking for a job but it feels difficult to justify my work-from-home requirement when the official guidance says that I ‘do not need to shield.’

Because of my leukaemia I haven’t worked for a year, and I’m likely to continue suffering financially for as long as coronavirus is a part of all our lives. This is on top of the huge emotional burden of going through cancer treatment, cutting myself off from loved ones and dealing with the overwhelming uncertainty of simply being alive at this moment in history. I actually feel strangely glad not to have a job to go back to; if I did, I might have the added anxiety of having to choose between my income and my health.  

It may seem like there are no good options at the moment, but I am sure that choosing to protect the most vulnerable in our society is the right thing to do.

I am as devastated as everyone else about the impact of Covid on jobs and the decimation of entire industries, but I know that if the country were to carry on as normal, I’d be fearing for my life this winter. I feel grateful every day to those who are making sacrifices to protect me and other high-risk individuals. It may seem like there are no good options at the moment, but I am sure that choosing to protect the most vulnerable in our society is the right thing to do. While I welcome this week’s new restrictions, the government must also commit to extending furlough and other support schemes (with specific considerations for working-age shielders) if the population as a whole is to get on board with the enormous sacrifices being demanded of them.  

People who were shielded during the peak of this crisis were both legally protected and financially supported. Shielding was advice, not the law, but it meant that we didn’t have to go out to work, and we were able to request free food parcels. Now despite the increasing case numbers and the tightening of restrictions, nothing is being done for those who are most vulnerable to the virus. ‘You do not need to shield’ feels to me like another way of saying ‘we’re not going to protect or support you.’ The potential consequences of this are catastrophic.

Jenni Elbourne is a freelance writer.


Original Source Article »

share on Twitter Like UK: England: Britain’s Preparing For A Second Wave. But Shielders Like Me Are Being Left Behind | The Huffington Post. on Facebook

+++

Pakistan: Karachi: Anti-polio drive achieves 94% of target | The Express Tribune.

[September 29, 2020] [APP]

The anti-polio campaign carried out in the city over the past week had achieved over 94 per cent of its set target, claimed Karachi Commissioner Sohail Rajput on Monday. The campaign, which began on September 21 and ended on September 28, achieved 9 per cent more of the set goal as compared to the drive conducted last month, revealed a report prepared by the anti-polio task force. As many as 1.7 million children under the age of five years were administered oral polio vaccines in different parts of the city, he shared. Moreover, around 287,739 children were administered the vaccination in the high-risk union councils, 15 per cent more than in the previous campaign in these UCs. Rajput announced that a three-day anti-polio drive would soon be launched for children who were not immunised during this campaign.


Original Source Article »

share on Twitter Like Pakistan: Karachi: Anti-polio drive achieves 94% of target | The Express Tribune. on Facebook

+++

Eradicating polio from Pakistan: Multiple doses of vaccine needed to ensure immunity, say experts | DAWN.

[28 Sep 2020] Shahzeb Ahmed writes:

In 2017, Pakistan was on the brink of declaring victory against the polio virus. That year, the country, one of the last bastions of the virus in the world, had reported its lowest number of cases in almost three decades.

Three years down the line, health authorities — both local and international — are scratching their heads over how to mitigate the crisis. In the current year so far, the country has reported 72 polio virus cases — a far cry from the eight reported in 2017. The preceding year was even worse, when 134 cases were reported in 2019, sounding alarm bells across the world.

According to the Pakistan Polio Eradication Programme (PPEP), “conflict, political instability, hard-to-reach populations, and poor infrastructure continue to pose challenges to eradicating the disease”.

At the same time, the refusal cases have done tremendous damage. Over the years, various conspiracy theories have been floated with regards to the polio vaccine, ranging from “it causes impotency” to “it is a conspiracy of the West”.

While the PPEP has made a lot of effort to dispel the rumours and raise awareness on the importance of getting children vaccinated, the number of refusals remains alarmingly high. Earlier this year, for example, a health official told Dawn that there were 38,000 refusal cases in January which rose to 51,000 in February in Peshawar district, one of the virus reservoirs in the country.

Why frequent vaccination campaigns are important.

In this case, the official attributed the rise in refusal cases to frequent vaccination campaigns. However, frequent vaccination campaigns are organised because children require a certain minimum number doses of the oral poliovirus vaccine (OPV) to ensure their adequate protection against the disease.

Child specialist Dr Iqbal Memon says that in a country like Pakistan “15 or more [doses of OPV] are considered adequate protection”.

The OPV, explains Dr Memon, is cheaper, widely available and easier to administer, hence it is recommended for use in developing countries. “Given multiple times … it leads to better control against wild polio virus in sewage as well,” he says. The only challenge to its delivery is ensuring that the cold chain supply is maintained.

In contrast, says Dr Memon, the inactivated poliovirus vaccine (IPV) must be administered intravenously, which is a challenge because it must be done through trained hands. It is also more expensive and much harder to procure. In the case of IPVs however, a couple of doses are enough to ensure immunity.

“In Pakistan, we need both [OPV and IPV],” says Dr Memon. “Hence both are part of Pakistan's essential immunisation programme. Ideally, if IPV is available, two doses along with an OPV course would be appropriate,” he explains.

According to Dr Ali Faisal Saleem, an infectious diseases expert at the Children's Hospital at Aga Khan University Hospital, "OPVs are administered as oral drops, which boost the child's immunity and are hence more important in a country like Pakistan, where the polio virus is still prevalent." The IPV, on the other hand, aids the OPV in such cases, says Dr Saleem. He adds that without the OPV, the IPV dose would be ineffective.

Safe for newborns.

Asked if the vaccines are safe to be administered to newborns, Dr Memon says there were no known side effects and that it is safe to administer multiple doses of OPV even to newborns.

Dr Saleem agrees, saying, "OPV is administered to all newborns in Pakistan at the time of birth. That is called dose zero. Thereafter, the vaccine is given to children at six weeks, 10 weeks and 14 weeks, after which they can be administered the vaccine every time there is a routine immunisation campaign." It is completely safe to administer as many doses of OPV as possible, he reiterates.

Stressing the importance of the vaccine further, Dr Saleem points out that globally, polio has been eradicated from almost all countries through the OPV. "In Pakistan too, all children are supposed to be administered the OPV as part of their routine immunisation at birth."

Can the vaccine be administered on a sick child?

To another question whether the vaccines were safe to be administered to a child who may be otherwise unwell, Dr Memon advises that in cases of mild illnesses, there is no issue with administering the vaccine.

However, he advises that if a child is sick enough to be admitted to a hospital, then it is recommended that the vaccine be administered once the child has recovered enough to no longer require hospitalisation .

With Nigeria having been declared polio-free last month, Pakistan and Afghanistan remain the only two countries that still have the disease.

The world’s eyes are focused on Pakistan and as are our health authorities in efforts to eradicate the virus. Now it's up to the parents and society as a whole to cooperate and encourage a culture of getting children vaccinated not only against polio but against all other vaccine-preventable diseases that can impact them.


Original Source Article »

share on Twitter Like Eradicating polio from Pakistan: Multiple doses of vaccine needed to ensure immunity, say experts | DAWN. on Facebook

+++

Whitepaper: Rapid paper-strip COVID contagiousness tests can reopen schools and the economy | RapidTests.Org.

Last month, the FDA approved the Abbott BinaxNOW, a rapid test that can be performed with a simple nasal swab.

While this is a step in the right direction, it is far short of what we need. The test requires a prescription, and it is only going to be produced at 1 million per day.

If we want to reopen schools, we need 20 million tests per day, available without prescription. Several manufacturers are capable of getting to this scale, but are choosing not to because of financial and regulatory uncertainty.

The technology is ready. We just need the will to deploy it. To read more, please see our short white paper, which we released last week.

https://www.rapidtests.org/s/whitepaper.pdf

Chris Said


Original Source Article »

share on Twitter Like Whitepaper: Rapid paper-strip COVID contagiousness tests can reopen schools and the economy | RapidTests.Org. on Facebook

+++

Somalia Polio Flash Update: Week 38 2020 | ReliefWeb.

[Situation Report] [Sources: UNICEF WHO] [Posted: 29 Sep 2020] [Originally Published: 29 Sep 2020]

• One case of polio, currently classified as an ambiguous vaccine-derived poliovirus type 2 (aVDPV2), was confirmed this week, with date of onset on 18 September 2020. The affected child lives in an accessible village in Borama District, Awdal region. This case is not genetically linked to any other VDPV2 viruses detected in Somalia.

• In total, 19* children with cVDPV have been identified across Somalia since the initial detection of the ongoing cVDPV2 and cVDPV3 outbreaks in late 2017.

• No cVDPV2 positive environmental samples were reported this week. 20 cVDPV2 positive environmental samples have been reported so far in 2020, including two from ad-hoc sites in Baidoa.

• This ongoing isolation of poliovirus from both the environment and cases suggests continuing transmission of cVDPV2 among the population.

• Steps taken in response to recent detection of cases include detailed case investigations, sensitizing health workers to acute flaccid paralysis, and intensified active case search.

• From 20 to 23 September, a mOPV2 case response, which has been postponed since March 2020, resumed with COVID-19-preventative measures in place. This house to house campaign took place in south and central zones of Somalia, with the aim of reaching 1.65 million children.

• Comprehensive communications for development activities took place to support the campaign, supported by 1695 community mobilizers. Activities included deploying sound trucks, radio spots, poster distribution and engaging community elders to spread awareness of the importance of vaccination.

• Forty-five new measles cases were reported this week, underlining the vulnerability of many unvaccinated Somali children to common childhood illnesses.


Download document (PDF | 486.83 KB)


Original Source Article »

share on Twitter Like Somalia Polio Flash Update: Week 38 2020 | ReliefWeb. on Facebook

+++

Pakistan: Polio refusal cases covered, claims Rawalpindi administration | The Nation.

[September 29, 2020] [APP]

RAWALPINDI    -    The district administration Monday claimed to cover all polio refusal cases whose parents refused vaccination to their children during a five-day anti-polio drive concluded on September 25.

On the direction of Deputy Commissioner Capt. (Retd) Anwar-ul-Haq, all the assistant commissioners remained active to persuade the parents who refused to vaccinate their children against polio.   Assistant Commissioner (AC) Saddar paid a visit to Union Councils 12, 23 and 32 and administered anti-polio drops to children after convincing their parents.

Meanwhile, the ACs of Taxila and Gujar Khan visited their respective areas and administered anti-polio drops to children of reluctant parents with the help of local ulemas and imams of the mosques.


Original Source Article »

share on Twitter Like Pakistan: Polio refusal cases covered, claims Rawalpindi administration | The Nation. on Facebook

+++

Genetic Diversity Analysis of Coxsackievirus A8 Circulating in China and Worldwide Reveals a Highly Divergent Genotype | Viruses.

[Open Access] [Received: 7 September 2020 / Revised: 21 September 2020 / Accepted: 22 September 2020 / Published: 23 September 2020]

Abstract.

Coxsackievirus A8 (CV-A8) is one of the pathogens associated with hand, foot and mouth disease (HFMD) and herpangina (HA), occasionally leading to severe neurological disorders such as acute flaccid paralysis (AFP). Only one study aimed at CV-A8 has been published to date, and only 12 whole-genome sequences are publicly available. In this study, complete genome sequences from 11 CV-A8 strains isolated from HFMD patients in extensive regions from China between 2013 and 2018 were determined, and all sequences from GenBank were retrieved. A phylogenetic analysis based on a total of 34 complete VP1 sequences of CV-A8 revealed five genotypes: A, B, C, D and E. The newly emerging genotype E presented a highly phylogenetic divergence compared with the other genotypes and was composed of the majority of the strains sequenced in this study. Markov chain Monte Carlo (MCMC) analysis revealed that genotype E has been evolving for nearly a century and somehow arose in approximately 2010. The Bayesian skyline plot showed that the population size of CV-A8 has experienced three dynamic fluctuations since 2001. Amino acid residues of VP1100N103Y240T and 241V, which were embedded in the potential capsid loops of genotype E, might enhance genotype E adaption to the human hosts. The CV-A8 whole genomes displayed significant intra-genotypic genetic diversity in the non-capsid region, and a total of six recombinant lineages were detected. The Chinese viruses from genotype E might have emerged recently from recombining with European CV-A6 strains. CV-A8 is a less important HFMD pathogen, and the capsid gene diversity and non-capsid recombination variety observed in CV-A8 strains indicated that the constant generation of deleterious genomes and a constant selection pressure against these deleterious mutations is still ongoing within CV-A8 quasispecies. It is possible that CV-A8 could become an important pathogen in the HFMD spectrum in the future. Further surveillance of CV-A8 is greatly needed.


Original Source Article »

share on Twitter Like Genetic Diversity Analysis of Coxsackievirus A8 Circulating in China and Worldwide Reveals a Highly Divergent Genotype | Viruses. on Facebook

+++

Afghanistan - campaign launches to vaccinate 2 million children against polio | MENAFN Business.

[9/28/2020 2:16:38 PM]

(MENAFN - Afghanistan Times) AT News

KABUL: Ministry of Public Health in a joint venture with its health partners has started anti-polio campaign in 10 provinces.

The campaign started from Monday and will be continued for five days, the ministry said in a statement.

Around two million children under five years will receive immunization drops and vaccinates against polio disease in this round in 112 districts of Paktia, Paktika, Khost, Ghazni, Logar, Maidan Wardak, Parwan, Kunduz, Baghlan and Nuristan provinces, added the statement.

Acting Minister of Public Health Dr. Jawad Osmani termed launch of the anti-polio campaign important and said that polio virus is a serious threat against children health.

He said that fortunately a good and safe vaccine is available against this disease, which through campaign children receive immunization drops and vaccinates freely by volunteer health workers.

Mr. Osmani called on parents to seriously consider the threats of the polio virus like coronavirus and vaccine their children against polio virus in each round of campaign in order to lead toward elimination of polio virus in the country.

Since the beginning of the year till now, 47 polio cases have been recorded across the country, which out of 33 cases in south region, seven cases in west region, three in southeastern region, two in eastern and one case in each north and northeastern reported.

Polio is a disease that paralysis and even kills and it won't be cured, so anti-polio vaccine is the only effective and safety way to prevent children from the disease. All children must take the anti-polio vaccine till five years old.

MENAFN2809202001690000ID1100870255


Original Source Article »

share on Twitter Like Afghanistan - campaign launches to vaccinate 2 million children against polio | MENAFN Business. on Facebook

+++

Podcast and Video: TWiV 667: Building a better virus trap | This Week in Virology.

[September 27, 2020]

Daniel Griffin provides a clinical report on COVID-19, review of the phase I and II trials of the Russian prime-boost vaccine, a mouse model that recapitulates age-dependent severe disease, and listener questions.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, and Rich Condit

Guest: Daniel Griffin

Watch 'virtual roundtable'; discussion on YouTube video [2:45:14]: https://youtu.be/q13aFM0Jp4w

or

Listen to Podcast via source article

or

Download TWiV 667 (99 MB .mp3, 165 min)
Subscribe (free): iTunesGoogle PodcastsRSSemail

Become a patron of TWiV!

Links for this episode

Weekly Science Picks 2:28:50

Dickson – Rewilding Europe
Alan – How to Do Nothing by Jenny Odell
Rich – Gene drive engineered mosquitoes
Vincent – TWiEVO 60 with 12 guests!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv


Original Source Article »

share on Twitter Like Podcast and Video: TWiV 667: Building a better virus trap | This Week in Virology. on Facebook

+++

Copyright © 2020 Chris Salter, All rights reserved.
Email Marketing Powered by Mailchimp