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A review of the safety of vaccines used in routine immunization in Africa | African Health Sciences | PubMed Central.

[Open Access] [2020 Mar; 20(1): 227–237]

Abstract.

Background.

Despite the significant role played by vaccines in global health, concerns over vaccine safety have increased tremendously over the years. There have been occasions where vaccines have caused rare, adverse reactions some of which have led to hospitalizations and even death. It is therefore important to establish the safety profile of routinely used vaccines in order to allay fears pertaining to their use.

Objectives.

This review was aimed at pooling together the safety data of selected vaccines used for routine immunization in Africa, a region of the world with paucity of vaccine safety data.

Methods.

Adverse Events Following Immunization safety data was searched for rotavirus, yellow fever, measles, rubella, tuberculosis (Bacillus Calmette Guerin-BCG), pneumococcal, Haemophilus Influenza type b, polio, meningococcal and the influenza A (H1N1) vaccines in PUBMED, Google Scholar, Clinical trials.gov and Cochrane controlled register of trials databases.

Results.

A total of twenty-four serious AEFIs and twenty-three minor AEFIs were identified from the review. The strength of association between AEFIs and vaccine was high for tuberculosis vaccine and moderate for all other vaccines.

Conclusion.

Even though AEFIs (including mild and severe) were identified in the review, all the vaccines studied were generally well tolerated.


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Pakistan: First Polio Campaign Of 2021 To Begin Tomorrow Across Balochistan | Quetta Voice.

[Jan 10, 2021]

First polio campaign of 2021 to begin tomorrow across BalochistanPolio drops being administered to a child in Quetta: Photo Ashraf Khan

QUETTA: First anti-polio campaign of the year 2021 would begin in all 33 districts of Balochistan from tomorrow (Monday). Rashid Razzaq, the Chief of Emergency Operation Cell (EOC) said all arrangements finalized and thousands of teams formed to launch campaign in the province.

Over 2.4 million children under the age of five years would be administered anti-polio drops in Quetta and other 32 districts of Balochistan, Mr. Razzaq informed. The new campaign has come after Balochistan reported 26 cases of the crippling virus during the year 2020.

Quetta, Pishin, Killa Abdullah reported 16 out of 26 polio cases last year. 

Sources in the health department said 16 out of a total of 26 cases reported from Quetta, Pishin, and Killa Abdullah districts of Balochistan. The three districts considered to be high-risk areas when it comes to the presence of poliovirus.

10,533 teams have been formed to make sure the success of the anti-polio campaign. The children would be provided polio drops at national highways, railway stations, and airports. “Religious scholars and political parties role crucial in battling the poliovirus“, Rashid Razzaq said.

Committees formed to convince parents refusing polio drops to their children. 

The government has also formed committees comprising religious scholars, tribal elders, and political figures to convince the parents refusing polio drops to their children under the age of five years.

Security has also been tightened across Balochistan to avoid the occurrence of any untoward incident during the polio campaign. In the past, polio volunteers and workers have been targeted in Quetta, Pishin, and other parts of Balochistan. Levies and policemen would be deployed at all polio centers to ensure peace on the eve of the anti-polio campaign. The Balochistan government has put all departments on high alert to eradicate the crippling virus from the province.


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Podcast and Video: TWiV 704: COVID-19 clinical update #44 with Dr. Daniel Griffin | This Week in Virology.

Published January 9, 2021; Recorded January 7, 2021]

TWiV 704: COVID-19 clinical update #44 with Dr. Daniel Griffin

In this COVID-19 clinical update, Daniel Griffin summarizes current status of vaccination in the US, discusses a study on convalescent sera from Argentina, use of remdesivir in patients with kidney disease, and provides further considerations on the use of Ct values in patient management.

Hosts: Daniel Griffin and Vincent Racaniello

Watch on YouTube video [32:17]: https://youtu.be/rlOjQ_kzRgw

or

Listen to Podcast via source article

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Download TWiV 704 (19 MB .mp3, 32 min)
Subscribe (free): iTunesGoogle PodcastsRSSemail

Become a patron of TWiV!

Links for this episode

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv


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