Workshop Invitation

How certain are we?

Progress in adapting systematic review methods to environmental health assessments

On-Line Workshop Invitation, 15 June 2020. Systematic review methods for environmental health assessments have come on a long way in the last 5 years. EBTC is please to announce that, in collaboration with the GRADE Working Group, we will be holding an on-line workshop where world-leading practitioners in SR methods will be discussing where next for the methodology.

We have an exciting panel of speakers from IARC, the US EPA, the WHO, the Swiss Centre for Applied Human Toxicology, and INRA (France).

To maximise the opportunity for global participation, and minimise webinar burn-out, the workshop is scheduled over two 90-minute sessions on 15 June. The first session covers the incorporation of mechanistic data in systematic reviews; the second how to assess certainty in environmental health evidence.

While the webinar is open to all, for security reasons you will need to register in order to participate. Please follow the links below:

Session details

Session 1 (8am EST): Incorporating mechanistic data in
environmental health systematic reviews
(register here)
  1. Applying SR methods to the task of developing knowledge of biological mechanisms by which environmental exposures cause adverse health outcomes (Dr Michelle Angrish, US EPA)
  2. Utilising mechanistic frameworks in defining the problem and eligibility criteria of a systematic review (Mr Nicolas Roth, Swiss Centre for Applied Human Toxicology)
  3. Incorporating mechanistic data in IARC carcinogenicity assessments using the key characteristics approach (Dr Kate Guyton, IARC)
  4. Thoughts and responses from the GRADE Working Group experience, plus moderated panel session. (Prof. Holger Schünemann, Dr Rebecca Morgan)
Session 2 (11am EST). Assessing certainty of the
evidence in environmental health contexts
 (register here)
  1. WHO experience in adapting the GRADE Framework to assessing certainty of the evidence in SRs of prevalence studies (Dr Frank Pega, WHO)
  2. US EPA IRIS Program approach to assessing certainty of the evidence, as conducted in the recent SRs of human health effects of exposure to phthalates (Dr Beth Radke, Dr Erin Yost, US EPA)
  3. Experience in integrating mechanistic data and using the NTP OHAT certainty framework in systematic reviews of the effect of organochlorine exposure on endometriosis (Dr German Cano Sancho, INRA)
  4. Thoughts and responses from GRADE Working Group experience, plua moderated panel session (Prof. Holger Schünemann, Dr Rebecca Morgan)
The Evidence-Based Toxicology Collaboration is an open international network of academic, government, non-profit and industry organizations, formed to foster collaborative development and adoption of evidence-based methodologies in toxicology. The EBTC is governed by the Board of Trustees.
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