EBTC EFSA workshop on AOPs
2-3 October 2019. EBTC organized, together with the European Food Safety Authority (EFSA), a two-day expert meeting on applying evidence-based methods to the development, assessment and implementation of adverse outcome pathways (AOPs).
The meeting, which took place in Parma (Italy), was a follow-up to the one-day workshop that EBTC organized in collaboration with the GRADE Working Group on 12 June in Hamilton (Canada).
The meeting in Parma was intended to continue and deepen the discussions started in Hamilton. To that end, the meeting revolved around three related themes:
- Literature-based AOP development
- Assessing certainty in AOPs, and
- Integrating certainty in AOPs and non-animal evidence into decision frameworks.
38 experts from different backgrounds participated in the workshop. After short general and thematic introductions, the themes were explored in detail in a series of break-out sessions.
The overall conclusion of the workshop was that evidence-based approaches do have a high potential to contribute to the development, assessment and implementation of AOPs, but that to optimize that contribution more in-depth research is required.
The results of the workshop will be be summarized in a workshop report and will form the basis for several follow-up manuscripts.
The workshop was supported by t4, the transatlantic think tank for toxicology, which is sponsored by the Doerenkamp-Zbinden Foundation.