EBTC 10th Anniversary Symposium:
10am-12pm EST, Thursday 11 November 2021

Evidence-based toxicology: past, present, and future

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EBTC was founded in 2011, so we have just turned 10! Entering our next decade, we would like to look back at the history of evidence-based methods in toxicology, how EBTC has contributed to the field, hear our stakeholders and members' perspectives on where they are on this journey, and get feedback on what EBTC's role in the next decade should be.

Agenda

• Introduction (Dr Marty Stephens)
• History of Evidence-based Toxicology movement and application in diverse fields (Professor Thomas Hartung, Founder of EBTC)

Break and fun quiz!

• History of implementation of Systematic Review methods at US EPA IRIS (Dr Kris Thayer, Director, Chemical & Pollutant Assessment Division, US Environmental Protection Agency)
• Systematic Review methodologies at EFSA (Dr Didier Verloo, Head of Assessment and methodological support Unit, EFSA)
• Certainty in evidence for environmental health claims (Professor Holger Schunemann, Director, McMaster GRADE Centre and Cochrane Canada)
• Artificial Intelligence and the future of EBT (Dr Michelle Angrish, Toxicologist, US EPA) 

Panel with users of evidence, including: Dr Richard Brown (WHO), Dr Tala Henry (US EPA, TBC)), Dr Bette Meek (Uiversity of Ottawa, OECD AOP program). Moderated by Jack Fowle, EBTC Board Chair moderator.

New publication

Improving the quality of toxicology and environmental health systematic reviews: What journal editors can do

• Click here to read (open access)

In 2019 EBTC convened a group of editors, systematic reviewers, and scientific publishing specialists to discuss what can be done by journals to raise publishing standards for toxicology and environmental health SRs.

They came up with 58 potential interventions relating to how journals could intervene to improve SR publications. 26 were shortlisted for being potentially effective, and 5 were selected as readily implementable and likely to have significant, immediate impact.

You can read what they were in the published manuscript that came out earlier this summer, here: https://doi.org/10.14573/altex.2106111 

Workshop report

Evidence-based methods, mechanistic frameworks, non-animal test methods

• Click here to read (open access)

This EBTC-sponsored workshop explored multiple aspects of how evidence-based methods can be applied to construct mechanistic frameworks for the development and use of non-animal toxicity tests.

Participants included the European Food Safety Authority, US Environmental Protection Agency, the OECD, GRADE, and commercial research and scientific consultancies including ICF and RTI International.

You can read about what the workshop discussed and concluded in the workshop report, available here: https://doi.org/10.14573/altex.2101211